DS-01® Daily Synbiotic
DS-01®
Daily Synbiotic
DS-01®
Daily Synbiotic
Reviews
The clinically proven, 24 strain probiotic + prebiotic for daily gut health, digestive relief, and whole body benefits.*
$49.99
30-day supply delivered monthly.
Pause or cancel anytime.
Start Now
30-day risk-free guarantee. Free US shipping.
Benefits*
  • Reduces bloating and gas within 1 week
  • Improves regularity and makes pooping easier within 2 weeks
  • Supports immune, skin, and heart health
  • Proven effective in 4 double-blind clinical trials
Ingredients
  • 24 strains, 53.6 billion AFU
  • Third-party tested for quality, pesticides, and allergens
  • Vegan and low FODMAP diet compatible
  • No refrigeration required
Bundle + Save 25%
Add DM-02 Daily Multivitamin to your routine and save on your first order.
$67.48 $89.98
Add
The complete probiotic that delivers results in just 7 days.
The complete probiotic that delivers results in just 7 days.
See Clinical Evidence
7 DAYS
Reduces Bloating and Gas
  • Clinically proven to reduce bloating
  • Alleviates excess gas
  • Eases digestive discomfort
2 WEEKS
Supports Healthy Regularity*
  • Promotes daily poops
  • Reduces occasional constipation
4 WEEKS
Smooths + Clears Skin*
  • Supports clear, healthy skin
  • Reduces wrinkles and signs of aging
  • Enhances the skin barrier
3 MONTHS
Immune + Heart Support*
  • Promotes immune system resilience
  • Balances healthy cholesterol
  • Supports healthy aging
The DS-01® Difference
Our formulation prioritizes strain diversity and survivability, so you get clinically proven results, not empty promises.
Dr. Zain Kassam, MD, MPH
Chief Medical Officer, Seed Health
24 Diverse Probiotic Strains
Research-derived doses for microbial diversity, the foundation of a healthy gut.
Engineered to Survive
Proprietary ViaCap® technology safeguards probiotics during the journey to the colon.
Antioxidant-Promoting Prebiotic
Non-fiber based prebiotic (unlike many found in food or drinks) that feeds beneficial gut microbes.
4 Gold-Standard Clinical Trials
Scientifically validated by experts as a complete formulation, four different times.
Many probiotics don’t make it to the gut alive. DS-01® does.
ViaCap® Delivery Technology
ViaCap® Delivery Technology
Strengthens your gut at the source for lasting relief.
DS-01® outperforms other probiotics.
DS-01®
Others
24 clinically studied probiotic strains
5 or less strains, rarely tested clinically
Engineered for precision delivery to the colon
Rarely reaches the colon
Third-party tested for pesticides, allergens, and heavy metals
Rare
Vegan, gluten- and nut-tested, low FODMAP
Rare
Strains that work harder for your whole body.
Chosen for their ability to improve gut function and build whole body health.
Gut + Immune Health Blend
38.7 BILLION AFU
Probiotic blend for digestive health, gut barrier integrity, and healthy immune response.
Supporting strains:
Bifidobacterium breve SD-BR3-IT.
Ligilactobacillus salivarius SD-LS1-IT
Bifidobacterium longum SD-BB536-JP
Skin Health Blend
3.34 BILLION AFU
Probiotic blend that improves clarity, texture, and signs of aging in 12 weeks.
Supporting strains:
Bifidobacterium longum SD-CECT7347-SP
Ligilactobacillus salivarius SD-LS1-IT
Heart Health Blend
4.21 BILLION AFU
Supports healthy, balanced cholesterol levels.
Supporting strains:
Lactiplantibacillus plantarum SD-LPLDL-UK
Bifidobacterium lactis SD-MB2409-IT
Vegan
Gluten-Tested
Dairy-Tested
Soy-Tested
Nut-Tested
Shellfish-Tested
Sesame-Tested
Corn-Tested
Glyphosate / AMPA-Tested
No Binders
No Preservatives
Prop. 65 Compliant
Sustainably delivered, monthly.
Our refill pouches protect your DS-01® through transit while being gentler on our Earth.
We stand by our science.
30-Day Guarantee
If DS-01® doesn’t work for you, request a refund within 30 days of your order delivery for your money back.
Flexible Subscription
Easily reschedule your DS-01® deliveries or cancel your subscription any time.
Free US Shipping
US orders ship within 1-2 business days. International flat-rate.
Talk With Our Team of Experts
Our SciCare team is here to answer all of your science, health, and product-related questions.
Questions?
We’re here to help.
When will I feel something?
It is normal to feel effects in the digestive tract in as little as 24-48 hours. Other longer term benefits like cardiovascular health and gut immune function may take longer. As long as you continue your daily intake, those beneficial microbes are doing their work inside to program, sustain, and enhance your health.
How do I take DS-01® Daily Synbiotic?
Adults—take 2 capsules daily, all at once. Preferably on an empty stomach to limit exposure to digestive enzymes and bile salts. However, you know your body best—if it’s more comfortable for you to take with food, please feel free to do so.
Why should I take DS-01® Daily Synbiotic?
You are home to a community of trillions of microorganisms, including 38,000,000,000,000 bacteria that live in and on you. They perform critical functions like digesting food, managing inflammation, and synthesizing key vitamins, metabolites and neurotransmitters. This is the microbiome. By supplementing your gut microbial makeup, DS-01® provides benefits for both digestive and whole body health.
Can I take this with other supplements? What about medications?
DS-01® is safe to take with other supplements. There are no known contraindications with DS-01® and any over the counter or prescription medications, though we encourage you to double check with your physician before adding our product to your regimen.
What does DS-01® Daily Synbiotic do?
DS-01® contains probiotic strains that have been clinically and scientifically studied to provide benefits around gastrointestinal function, skin health, heart health, gut immune function, gut barrier integrity, and micronutrient synthesis.
Do I need to refrigerate my DS-01® Daily Synbiotic
No refrigeration necessary.
What does my subscription to DS-01® Daily Synbiotic include?
Your monthly subscription includes a 30-day supply of DS-01®. Your first month’s shipment is your Welcome Kit. It includes a reusable glass jar holding your first month’s supply, some Seed reading materials, and a complimentary travel vial that holds a week’s worth of your DS-01®, so you never miss a day on the go.
Is DS-01® Daily Synbiotic compatible with my diet or dietary restrictions?
DS-01® is tested for: Dairy, Gluten, Soy, GMOs, Nuts, Shellfish, Sesame, Glyphosate/AMPA, and 14 classes of allergens defined by European Food and Safety Authority (EFSA)

It adheres to the following diets: Vegan • Vegetarian • Ketogenic • Gluten-Free • Intermittent Fasting
What is your 30 day risk-free guarantee? Do you accept returns?
If for any reason you are not satisfied with your purchase, you may request a refund within 30 days of delivery of your first order. We’ll refund you for the full cost of the product less shipping, VAT, and duties—no questions asked. Refunds apply to your first order only, not any subsequent shipments. For all subsequent shipments, you may reschedule or cancel at any time in your account.

Note that Sustainable Refill Program orders are considered final sale 30 days after delivery.
Is DS-01® Daily Synbiotic safe to take while I'm pregnant or breastfeeding?
As with any dietary supplement or new health protocol contemplated during pregnancy or lactation, we recommend speaking with your physician or obstetrician before you start consuming DS-01® Daily Synbiotic.

Probiotics, in general, do not appear to pose any safety concerns for pregnant and lactating individuals. The current literature does not indicate an increase in adverse pregnancy outcomes when probiotics are used by healthy individuals.
Do you ship internationally?
Yes—we ship to many countries internationally.
DS-01® Daily Synbiotic
Clinical Trials
Only about 16% of supplements are clinically tested.
DS-01® has been clinically proven in 4 gold-standard, double-blind placebo controlled clinical trials.
In addition, DS-01®’s probiotic strains have been validated in 10, dose-matched gold-standard clinical trials.
The Impact of Clinical Proof
Double-blind, randomized, placebo-controlled trials (DBRCTs) are the gold standard in scientific research for various reasons, including:
  • Bias elimination
  • Control for placebo-effect
  • Validated efficacy
  • Regulatory compliance
By testing DS-01® as a full formulation, the entire product is meticulously inspected and validated for safety, tolerability, and efficacy.
Digestive Health
DS-01® is formulated to improve the frequency of your bowel movements, as well as increase stool consistency and comfort during evacuation.
Clinical Trial Results
  • In a 30-day study on select DS-01® strains, adults experiencing gastrointestinal troubles saw significant improvement in bowel movement frequency, consistency, and ease of defecation, compared to placebo.
  • DS-01®’s strains also demonstrated improvements in burning, discomfort, sense of complete emptying, and abdominal bloating.
Immune Health
DS-01® promotes a strong, resilient immune system. Dedicated strains support the gut-immune axis, which allows these systems to communicate effectively and strengthen overall immune function.
Clinical Trial Results
  • In a 12-week study using select DS-01® strains, participants showed a reduction in microbial translocation across the intestinal epithelial barrier and favorable circulating Th17:Treg and Th1:Th2 ratios. These findings indicate an appropriately responsive immunologic profile.
Skin Health
DS-01® is formulated with dedicated strains that support the gut-skin axis, which plays a key role in regulating inflammatory pathways between the gut and skin.
Clinical Trial Results
  • A 4-week study found DS-01®'s prebiotic significantly reduced wrinkle severity and demonstrated an overall shift in the skin microbiome, indicating a beneficial effect on the gut-skin axis.
  • A 12-week study of adults with functionally and aesthetically bothersome skin showed DS-01® strains not only improved skin appearance, but also raised quality of life scores.
Heart Health
DS-01® is formulated to help maintain healthy, in-range cholesterol and blood pressure levels. Select strains promote the production of beneficial metabolites in the gut, which supports healthy liver function and cholesterol balance.
Clinical Trial Results
  • In a 12-week study, DS-01® strains helped probiotic group participants maintain healthy, baseline LDL-C levels, compared to a placebo group that experienced LDL-C increases.
  • Additionally, the probiotic group demonstrated reinforcement of HDL-cholesterol and evidence of healthy triglyceride management within the 6-12 week timeframe.
Gut Barrier
DS-01® is formulated to strengthen and support a resilient gut barrier. Select strains replenish microflora in the gut in order to help rebuild a weakened microbiome.
Clinical Trial Results
  • In a 12-week study using select DS-01® strains, adults experiencing increased gut permeability showed significant reductions in circulating lipopolysaccharide (LPS), a marker of increased epithelial permeability, the cells which comprise the gut barrier.
  • DS-01® significantly reduced urinary lactulose excretion starting at 7 days and after 3 months of ongoing DS-01® use, compared to the placebo group— indicating both immediate and continued support for gut barrier integrity and function.
DS-01® Daily Synbiotic
Survivability
Many probiotics—like gummies, powders, and drinks—dissolve during digestion. DS-01®’s proprietary ViaCap® system is engineered to protect probiotic strains from stomach acid, digestive enzymes, and bile.
ViaCap® Technology
Our proprietary dual-capsule system is built for a timed release to the colon: the prebiotic outer capsule releases in the upper GI tract and the probiotic inner capsule continues to the large intestine.
ViaCap capsule technology showing nested capsule design with black and white capsules
  • Outer capsule made from cellulose protects probiotics and prebiotics as they travel through the GI tract.
  • Plant-based formula—no synthetic coatings like similar cap-in-cap systems.
  • Engineered for precision delivery to the colon, where bacteria is needed to work effectively.
Digestive Survivability Testing (SHIME®)
To evaluate the survival of our probiotics, we use a Simulator of the Human Intestinal Microbial Ecosystem (SHIME®)—the closest simulation of the human gastrointestinal system. It recreates the physiological conditions of digestion (food uptake, peristalsis, digestive enzymes, pancreatic and bile acids) and time spent in each step to represent the dynamic microbial conditions of the human gastrointestinal tract.
DS-01® Daily Synbiotic
Strains + Ingredients
DS-01® is formulated with 24 scientifically and clinically studied probiotic strains and a patented, non-fermenting prebiotic.
53.6 billion AFU. No refrigeration required.
Strains
Probiotic inner capsule with white powder
Probiotic Inner Capsule
Proprietary formulation consisting of 24 probiotic strains (53.6 billion AFU) validated through strain-specific research and free of all 14 classes of allergens identified by the European Food Safety Authority (EFSA).
Digestive Health / Gastrointestinal Immunity / Gut Barrier Integrity Probiotic Blend
38.7 Billion AFU
Bifidobacterium longum SD-BB536-JP
Bifidobacterium breve SD-LP1-IT
Lactiplantibacillus plantarum SD-LP1-IT
Lactisaceibacillus rhamnosus SD-LR6-IT
Lactisaceibacillus rhamnosus HRVD113-US
Bifidobacterium infantis SD-M63-JP
Bifidobacterium lactis SD-BS5-IT
Bifidobacterium lactis HRVD524-US
Lactobacillus crispatus SD-LCR01-IT
Lactisaceibacillus casei HRVD300-US
Bifidobacterium breve HRVD521-US
Bifidobacterium longum HRVD90b-US
Bifidobacterium lactis SD150-BE
Limosilactobacillus fermentum SD-LF8-IT
Lactisaceibacillus rhamnosus SD-GG-BE
Limosilactobacillus reuteri RD830-FR
Dermatological Health Probiotic Blend
3.34 Billion AFU
Ligilactobacillus salivarius SD-LS1-IT
Bifidobacterium lactis SD-CECT8145-SP
Bifidobacterium longum SD-CECT7347-SP
Lacticaseibacillus casei SD-CECT9104-SP
Cardiovascular Health Probiotic Blend
4.21 Billion AFU
Lactiplantibacillus plantarum SD-LPLDL-UK
Bifidobacterium lactis SD-MB2409-IT
Micronutrient Synthesis Probiotic Blend
7.32 Billion AFU
Bifidobacterium adolescentis SD-BA5-IT
Limosilactobacillus reuteri SD-LRE2-IT
Microbiota-Accessible Polyphenolic Precursors™️ [MAPP]
400MG

Indian Pomegranate [whole fruit] (Punica granatum) (>40% Polyphenolic + Phenolic Bioactives)

Probiotic inner capsule with white powder
Prebiotic Outer Capsule
Our prebiotic formulation consists of punicalagins concentrated from Indian pomegranate—biotransformed by gut microbes into powerful metabolites for human health.
Other Ingredients
Vegan outer [hypromellose, chlorophyllin] and inner [hypromellose, water] capsulesOrganic rice fiber
Organic rice fiber
Organic rice extract blend
Safety + Testing
DS-01® is held to a superior standard of quality and safety, undergoing 50+ checkpoints throughout the production process testing for purity, potency, and contaminants.
Vegan
No Preservatives
No Binders
Dairy-Tested
Gluten-Tested
Nut-Tested
Soy-Tested
Shellfish-Tested
Sesame-Tested
Corn-Tested
Prop. 65 Compliant
Glyphosate / AMPA-Tested
Supplement Facts
DS-01® Daily Synbiotic
Strains + Ingredients
DS-01® is formulated with 24 scientifically studied probiotic strains with a patented, non-fermenting prebiotic.
53.6 Billion AFU. No refrigeration required.
Safety + Testing
Vegan
Gluten-tested
Dairy-tested
Soy-tested
Nut-tested
Shellfish-tested
Sesame-tested
Corn-tested
Glyphosate / AMPA-tested
No Binders
No Preservatives
Prop. 65 Compliant
Supplement Facts
DS-01® Daily Synbiotic
DS-01®
Daily Synbiotic
DS-01®
Daily Synbiotic
Reviews
The clinically proven, 24 strain probiotic + prebiotic for daily gut health, digestive relief, and whole body benefits.*
$49.99
30-day supply delivered monthly.
Pause or cancel anytime.
Start Now
30-day risk-free guarantee. Free US shipping.
Benefits*
  • Reduces bloating and gas within 1 week
  • Improves regularity and makes pooping easier within 2 weeks
  • Supports immune, skin, and heart health
  • Proven effective in 4 double-blind clinical trials
Ingredients
  • 24 strains, 53.6 billion AFU
  • Third-party tested for quality, pesticides, and allergens
  • Vegan and low FODMAP diet compatible
  • No refrigeration required
Bundle + Save 25%
Add DM-02 Daily Multivitamin to your routine and save on your first order.
$67.48 $89.98
Add
The complete probiotic that delivers results in just 7 days.
The complete probiotic that delivers results in just 7 days.
See Clinical Evidence
7 DAYS
Reduces Bloating and Gas
  • Clinically proven to reduce bloating
  • Alleviates excess gas
  • Eases digestive discomfort
2 WEEKS
Supports Healthy Regularity*
  • Promotes daily poops
  • Reduces occasional constipation
4 WEEKS
Smooths + Clears Skin*
  • Supports clear, healthy skin
  • Reduces wrinkles and signs of aging
  • Enhances the skin barrier
3 MONTHS
Immune + Heart Support*
  • Promotes immune system resilience
  • Balances healthy cholesterol
  • Supports healthy aging
The DS-01® Difference
Our formulation prioritizes strain diversity and survivability, so you get clinically proven results, not empty promises.
Dr. Zain Kassam, MD, MPH
Chief Medical Officer, Seed Health
24 Diverse Probiotic Strains
Research-derived doses for microbial diversity, the foundation of a healthy gut.
Engineered to Survive
Proprietary ViaCap® technology safeguards probiotics during the journey to the colon.
Antioxidant-Promoting Prebiotic
Non-fiber based prebiotic (unlike many found in food or drinks) that feeds beneficial gut microbes.
4 Gold-Standard Clinical Trials
Scientifically validated by experts as a complete formulation, four different times.
Many probiotics don’t make it to the gut alive. DS-01® does.
ViaCap® Delivery Technology
ViaCap® Delivery Technology
Strengthens your gut at the source for lasting relief.
DS-01® outperforms other probiotics.
DS-01®
Others
24 clinically studied probiotic strains
5 or less strains, rarely tested clinically
Engineered for precision delivery to the colon
Rarely reaches the colon
Third-party tested for pesticides, allergens, and heavy metals
Rare
Vegan, gluten- and nut-tested, low FODMAP
Rare
Strains that work harder for your whole body.
Chosen for their ability to improve gut function and build whole body health.
Gut + Immune Health Blend
38.7 BILLION AFU
Probiotic blend for digestive health, gut barrier integrity, and healthy immune response.
Supporting strains:
Bifidobacterium breve SD-BR3-IT.
Ligilactobacillus salivarius SD-LS1-IT
Bifidobacterium longum SD-BB536-JP
Skin Health Blend
3.34 BILLION AFU
Probiotic blend that improves clarity, texture, and signs of aging in 12 weeks.
Supporting strains:
Bifidobacterium longum SD-CECT7347-SP
Ligilactobacillus salivarius SD-LS1-IT
Heart Health Blend
4.21 BILLION AFU
Supports healthy, balanced cholesterol levels.
Supporting strains:
Lactiplantibacillus plantarum SD-LPLDL-UK
Bifidobacterium lactis SD-MB2409-IT
Vegan
Gluten-Tested
Dairy-Tested
Soy-Tested
Nut-Tested
Shellfish-Tested
Sesame-Tested
Corn-Tested
Glyphosate / AMPA-Tested
No Binders
No Preservatives
Prop. 65 Compliant
Sustainably delivered, monthly.
Our refill pouches protect your DS-01® through transit while being gentler on our Earth.
We stand by our science.
30-Day Guarantee
If DS-01® doesn’t work for you, request a refund within 30 days of your order delivery for your money back.
Flexible Subscription
Easily reschedule your DS-01® deliveries or cancel your subscription any time.
Free US Shipping
US orders ship within 1-2 business days. International flat-rate.
Talk With Our Team of Experts
Our SciCare team is here to answer all of your science, health, and product-related questions.
Questions?
We’re here to help.
When will I feel something?
It is normal to feel effects in the digestive tract in as little as 24-48 hours. Other longer term benefits like cardiovascular health and gut immune function may take longer. As long as you continue your daily intake, those beneficial microbes are doing their work inside to program, sustain, and enhance your health.
How do I take DS-01® Daily Synbiotic?
Adults—take 2 capsules daily, all at once. Preferably on an empty stomach to limit exposure to digestive enzymes and bile salts. However, you know your body best—if it’s more comfortable for you to take with food, please feel free to do so.
Why should I take DS-01® Daily Synbiotic?
You are home to a community of trillions of microorganisms, including 38,000,000,000,000 bacteria that live in and on you. They perform critical functions like digesting food, managing inflammation, and synthesizing key vitamins, metabolites and neurotransmitters. This is the microbiome. By supplementing your gut microbial makeup, DS-01® provides benefits for both digestive and whole body health.
Can I take this with other supplements? What about medications?
DS-01® is safe to take with other supplements. There are no known contraindications with DS-01® and any over the counter or prescription medications, though we encourage you to double check with your physician before adding our product to your regimen.
What does DS-01® Daily Synbiotic do?
DS-01® contains probiotic strains that have been clinically and scientifically studied to provide benefits around gastrointestinal function, skin health, heart health, gut immune function, gut barrier integrity, and micronutrient synthesis.
Do I need to refrigerate my DS-01® Daily Synbiotic
No refrigeration necessary.
What does my subscription to DS-01® Daily Synbiotic include?
Your monthly subscription includes a 30-day supply of DS-01®. Your first month’s shipment is your Welcome Kit. It includes a reusable glass jar holding your first month’s supply, some Seed reading materials, and a complimentary travel vial that holds a week’s worth of your DS-01®, so you never miss a day on the go.
Is DS-01® Daily Synbiotic compatible with my diet or dietary restrictions?
DS-01® is tested for: Dairy, Gluten, Soy, GMOs, Nuts, Shellfish, Sesame, Glyphosate/AMPA, and 14 classes of allergens defined by European Food and Safety Authority (EFSA)

It adheres to the following diets: Vegan • Vegetarian • Ketogenic • Gluten-Free • Intermittent Fasting
What is your 30 day risk-free guarantee? Do you accept returns?
If for any reason you are not satisfied with your purchase, you may request a refund within 30 days of delivery of your first order. We’ll refund you for the full cost of the product less shipping, VAT, and duties—no questions asked. Refunds apply to your first order only, not any subsequent shipments. For all subsequent shipments, you may reschedule or cancel at any time in your account.

Note that Sustainable Refill Program orders are considered final sale 30 days after delivery.
Is DS-01® Daily Synbiotic safe to take while I'm pregnant or breastfeeding?
As with any dietary supplement or new health protocol contemplated during pregnancy or lactation, we recommend speaking with your physician or obstetrician before you start consuming DS-01® Daily Synbiotic.

Probiotics, in general, do not appear to pose any safety concerns for pregnant and lactating individuals. The current literature does not indicate an increase in adverse pregnancy outcomes when probiotics are used by healthy individuals.
Do you ship internationally?
Yes—we ship to many countries internationally.
DS-01® Daily Synbiotic
Clinical Trials
Only about 16% of supplements are clinically tested.
DS-01® has been clinically proven in 4 gold-standard, double-blind placebo controlled clinical trials.
In addition, DS-01®’s probiotic strains have been validated in 10, dose-matched gold-standard clinical trials.
The Impact of Clinical Proof
Double-blind, randomized, placebo-controlled trials (DBRCTs) are the gold standard in scientific research for various reasons, including:
  • Bias elimination
  • Control for placebo-effect
  • Validated efficacy
  • Regulatory compliance
By testing DS-01® as a full formulation, the entire product is meticulously inspected and validated for safety, tolerability, and efficacy.
Digestive Health
DS-01® is formulated to improve the frequency of your bowel movements, as well as increase stool consistency and comfort during evacuation.
Clinical Trial Results
  • In a 30-day study on select DS-01® strains, adults experiencing gastrointestinal troubles saw significant improvement in bowel movement frequency, consistency, and ease of defecation, compared to placebo.
  • DS-01®’s strains also demonstrated improvements in burning, discomfort, sense of complete emptying, and abdominal bloating.
Immune Health
DS-01® promotes a strong, resilient immune system. Dedicated strains support the gut-immune axis, which allows these systems to communicate effectively and strengthen overall immune function.
Clinical Trial Results
  • In a 12-week study using select DS-01® strains, participants showed a reduction in microbial translocation across the intestinal epithelial barrier and favorable circulating Th17:Treg and Th1:Th2 ratios. These findings indicate an appropriately responsive immunologic profile.
Skin Health
DS-01® is formulated with dedicated strains that support the gut-skin axis, which plays a key role in regulating inflammatory pathways between the gut and skin.
Clinical Trial Results
  • A 4-week study found DS-01®'s prebiotic significantly reduced wrinkle severity and demonstrated an overall shift in the skin microbiome, indicating a beneficial effect on the gut-skin axis.
  • A 12-week study of adults with functionally and aesthetically bothersome skin showed DS-01® strains not only improved skin appearance, but also raised quality of life scores.
Heart Health
DS-01® is formulated to help maintain healthy, in-range cholesterol and blood pressure levels. Select strains promote the production of beneficial metabolites in the gut, which supports healthy liver function and cholesterol balance.
Clinical Trial Results
  • In a 12-week study, DS-01® strains helped probiotic group participants maintain healthy, baseline LDL-C levels, compared to a placebo group that experienced LDL-C increases.
  • Additionally, the probiotic group demonstrated reinforcement of HDL-cholesterol and evidence of healthy triglyceride management within the 6-12 week timeframe.
Gut Barrier
DS-01® is formulated to strengthen and support a resilient gut barrier. Select strains replenish microflora in the gut in order to help rebuild a weakened microbiome.
Clinical Trial Results
  • In a 12-week study using select DS-01® strains, adults experiencing increased gut permeability showed significant reductions in circulating lipopolysaccharide (LPS), a marker of increased epithelial permeability, the cells which comprise the gut barrier.
  • DS-01® significantly reduced urinary lactulose excretion starting at 7 days and after 3 months of ongoing DS-01® use, compared to the placebo group— indicating both immediate and continued support for gut barrier integrity and function.
DS-01® Daily Synbiotic
Survivability
Many probiotics—like gummies, powders, and drinks—dissolve during digestion. DS-01®’s proprietary ViaCap® system is engineered to protect probiotic strains from stomach acid, digestive enzymes, and bile.
ViaCap® Technology
Our proprietary dual-capsule system is built for a timed release to the colon: the prebiotic outer capsule releases in the upper GI tract and the probiotic inner capsule continues to the large intestine.
ViaCap capsule technology showing nested capsule design with black and white capsules
  • Outer capsule made from cellulose protects probiotics and prebiotics as they travel through the GI tract.
  • Plant-based formula—no synthetic coatings like similar cap-in-cap systems.
  • Engineered for precision delivery to the colon, where bacteria is needed to work effectively.
Digestive Survivability Testing (SHIME®)
To evaluate the survival of our probiotics, we use a Simulator of the Human Intestinal Microbial Ecosystem (SHIME®)—the closest simulation of the human gastrointestinal system. It recreates the physiological conditions of digestion (food uptake, peristalsis, digestive enzymes, pancreatic and bile acids) and time spent in each step to represent the dynamic microbial conditions of the human gastrointestinal tract.
DS-01® Daily Synbiotic
Strains + Ingredients
DS-01® is formulated with 24 scientifically and clinically studied probiotic strains and a patented, non-fermenting prebiotic.
53.6 billion AFU. No refrigeration required.
Strains
Probiotic inner capsule with white powder
Probiotic Inner Capsule
Proprietary formulation consisting of 24 probiotic strains (53.6 billion AFU) validated through strain-specific research and free of all 14 classes of allergens identified by the European Food Safety Authority (EFSA).
Digestive Health / Gastrointestinal Immunity / Gut Barrier Integrity Probiotic Blend
38.7 Billion AFU
Bifidobacterium longum SD-BB536-JP
Bifidobacterium breve SD-LP1-IT
Lactiplantibacillus plantarum SD-LP1-IT
Lactisaceibacillus rhamnosus SD-LR6-IT
Lactisaceibacillus rhamnosus HRVD113-US
Bifidobacterium infantis SD-M63-JP
Bifidobacterium lactis SD-BS5-IT
Bifidobacterium lactis HRVD524-US
Lactobacillus crispatus SD-LCR01-IT
Lactisaceibacillus casei HRVD300-US
Bifidobacterium breve HRVD521-US
Bifidobacterium longum HRVD90b-US
Bifidobacterium lactis SD150-BE
Limosilactobacillus fermentum SD-LF8-IT
Lactisaceibacillus rhamnosus SD-GG-BE
Limosilactobacillus reuteri RD830-FR
Dermatological Health Probiotic Blend
3.34 Billion AFU
Ligilactobacillus salivarius SD-LS1-IT
Bifidobacterium lactis SD-CECT8145-SP
Bifidobacterium longum SD-CECT7347-SP
Lacticaseibacillus casei SD-CECT9104-SP
Cardiovascular Health Probiotic Blend
4.21 Billion AFU
Lactiplantibacillus plantarum SD-LPLDL-UK
Bifidobacterium lactis SD-MB2409-IT
Micronutrient Synthesis Probiotic Blend
7.32 Billion AFU
Bifidobacterium adolescentis SD-BA5-IT
Limosilactobacillus reuteri SD-LRE2-IT
Microbiota-Accessible Polyphenolic Precursors™️ [MAPP]
400MG

Indian Pomegranate [whole fruit] (Punica granatum) (>40% Polyphenolic + Phenolic Bioactives)

Probiotic inner capsule with white powder
Prebiotic Outer Capsule
Our prebiotic formulation consists of punicalagins concentrated from Indian pomegranate—biotransformed by gut microbes into powerful metabolites for human health.
Other Ingredients
Vegan outer [hypromellose, chlorophyllin] and inner [hypromellose, water] capsulesOrganic rice fiber
Organic rice fiber
Organic rice extract blend
Safety + Testing
DS-01® is held to a superior standard of quality and safety, undergoing 50+ checkpoints throughout the production process testing for purity, potency, and contaminants.
Vegan
No Preservatives
No Binders
Dairy-Tested
Gluten-Tested
Nut-Tested
Soy-Tested
Shellfish-Tested
Sesame-Tested
Corn-Tested
Prop. 65 Compliant
Glyphosate / AMPA-Tested
Supplement Facts
DS-01® Daily Synbiotic
Strains + Ingredients
DS-01® is formulated with 24 scientifically studied probiotic strains with a patented, non-fermenting prebiotic.
53.6 Billion AFU. No refrigeration required.
Safety + Testing
Vegan
Gluten-tested
Dairy-tested
Soy-tested
Nut-tested
Shellfish-tested
Sesame-tested
Corn-tested
Glyphosate / AMPA-tested
No Binders
No Preservatives
Prop. 65 Compliant
Supplement Facts